Dejerine-Roussy (thalamic pain) syndrome – What are the signs and symptoms, relevant dDx., sequelae, work up, and treatment options?

Dejerine-Roussy syndrome is hypersensitivity to pain as a result of damage to the thalamus.

Sn. & Sx.:

• Hemianesthesia
• Allodynia and hyperalgesia
• Deep painful stimuli
• Persistent, spontaneous, burning pain contralateral to the lesion

dDx.:

• Complex regional pain syndrome
• Fibromyalgia

Sequelae:

• Impaired social and occupational functioning

Work up:

• Neurological exam

Tx.:

• Tricyclic antidepressants (Amitriptyline)

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This post was written by Omar Rifai